Second RECOMB Satellite Workshop on Computational Methods for SNPs and Haplotypes SCOPE: This meeting will focus on current research at the intersection of genetics, computer science, statistics, and related fields in gathering and analyzing SNP and haplotype data and applying it to problems in medicine and basic research. We plan to build on the success of the first RECOMB Satellite Meeting on Computational Methods for SNPs and Haplotypes in bringing together leading participants from widely divergent backgrounds to share their expertise and results. The recent availability of large-scale genotype data has created new possibilities for tracking down the currently elusive genetic risk factors of many complex diseases. Extensive data on human genetic variability in healthy and diseased individuals, predominantly in the form of single nucleotide polymorphisms (SNPs), is giving us the raw material we will need to locate genes and genetic variants that are associated with disease. Much recent attention has focused on the use of haplotypes --- evolutionarily conserved sets of contiguous polymorphisms --- as a way of exploiting regularities in the data sets to reduce the magnitude of the problem. Many questions remain about the nature of this haplotype conservation, how best to use it in disease inference studies, and how effective it will prove in practice. TOPICS TOPICS: Original research papers (including significant work-in-progress) or state-of-the-art surveys are solicited in all aspects of SNP and haplotype analysis and applications to medicine, including, but not limited to: - New methods for gathering genetic polymorphism data. - Understanding of the biological basis of genome structure. - Statistical techniques for the analysis of the data. - Computational methods for inferring genetic structure. - Applications to disease association and to medicine. - New genotype and haplotype data sets and their analysis. INVITED SPEAKERS: Confirmed speakers: Goncalo Abecasis, University of Michigan David Altshuler, Harvard Medical School & Whitehead Institute Carlos Bustamante, Cornell University Andrew Clark, Cornell University David Clayton, Cambridge Institute for Medical Research Mark Daly, Whitehead Institute Francisco de la Vega, Applied Biosystems Peter Donnelly, University of Oxford Stacey Gabriel, Whitehead Institute Sorin Istrail Applied Biosystems Jun Liu, Harvard University Rasmus Nielsen, Cornell University Magnus Nordborg, University of Southern California Kathryn Roeder, Carnegie Mellon University David Schwartz, University of Minnesota Ron Shamir, Tel Aviv University Mark Shriver, Penn State University Jeffrey Wall, University of Southern California SUBMISSIONS: Questions and electronic submissions can be sent by email to recomb-workshop@lists.andrew.cmu.edu. Your submission must be received in electronic form by 11:59pm (PDT) of December 6, 2003 for your submission to be considered. Due to the short turnaround time for reviewers, we will not be able to make exceptions to the deadline. Accepted papers will be compiled for a volume of Lecture Notes in Bioinformatics (http://www.springer.de/comp/lncs/index.html). Please prepare manuscripts according to the LNBI author specifications (http://www.springer.de/comp/lncs/authors.html). Papers should be at most 10 pages long, excluding title and abstract. If necessary, additional clearly marked appendices can be included but may not be read in review, at the discretion of the reviewers. IMPORTANT DATES: Submission Deadline: December 6, 2003 Notifications to Authors: December 15, 2003 Workshop: February 21-22, 2004 Information on participation, financial support, registration, accommodations, and travel can be found at: http://www.aladdin.cs.cmu.edu/workshops/recomb Steering Committee David Altshuler (chair), Massachusetts General Hospital Andrew G. Clark, Cornell University Sorin Istrail, Applied Biosystems Michael Waterman, University of Southern California Program Committee (Tentative) Goncalo Abecasis, University of Michigan David Altschuler, Harvard Medical School & Whitehead Institute Eric Anderson, NOAA Carlos Bustamante, Cornell University Andrew Clark, Cornell University David Clayton, University of Cambridge Mark Daly, Whitehead Institute Dan Gusfield, UC Davis Bjarni Halldorsson, Applied Biosystems Eran Halperin, Princeton University Sorin Istrail, Applied Biosystems Rasmus Nielsen, Cornell University Magnus Nordborg, University of Southern California Kathryn Roeder, Carnegie Mellon University David Schwartz, University of Minnesota Russell Schwartz, Carnegie Mellon University Fengzhu Sun, University of Southern California John Todd, University de Cambridge Francisco de la Vega, Applied Biosystems Jeffrey Wall, University of Southern California Michael Waterman, University of Southern California Organizing Committee Kathryn Roeder, Carnegie Mellon University Russell Schwartz, Carnegie Mellon University Eran Halperin, Princeton University This meeting is being organized and sponsored by the Aladdin Center at Carnegie Mellon University with generous support from Applied Biosystems.